New WHO document provides assessments of social mobilization and communication of HPV vaccine implementation in Latvia, Malaysia, and Rwanda in 2012 to understand the issues and solutions in different socioeconomic, cultural, religious, and regional settings. Discusses lessons learned a 2-day gathering to review HPV vaccine social mobilization and communication issues with both communications and new vaccine focal points in late February 2013. From the regions, they have multiple experiences from other countries (Bhutan, Mongolia, Romania, U.S., India, Pacific Island countries, etc.) that also informed their decisions.